Ketamine Therapy for Depression, PTSD, Anxiety, Chronic Pain, & Addiction in D.C., Maryland, & Virginia

Millions of Americans suffer from mood disorders and chronic pain. At Avesta Ketamine and Wellness, with clinics in McLean, Virginia, Bethesda, Maryland, and Washington DC, our providers work with our patients’ care teams to build the most efficacious treatment plan for the patient.

  • Our success rates in mood disorder patients aged 14-65 are 75-80%, in line with research

  • Research shows that ketamine can help individuals who have been treatment-resistant to other medications (Carboni et al., 2021)

  • We follow a research-based, safe and effective protocol created by Dr. Ladan Eshkevari that is individualized to each patient based on their response


    Dr. Ladan Eshkevari, PhD, CRNA, LAc, FAAN, is Founder and co-CEO of Avesta Ketamine Wellness.

    Dr. Eshkevari is a professor Emeritus at Georgetown University where she was full-time faculty for 25 years, educating graduate nursing and medical students. She earned her Bachelor of Science in Nursing with Honors from the University of Maryland and her Master of Science in nurse anesthesia from Columbia University in NYC. She earned her doctorate in physiology and biophysics from Georgetown University. She is an expert in the area of stress related depression, anxiety, anesthesia, pain management, and alternative medicine, and holds a diplomate degree in Traditional Chinese Medicine and Acupuncture.


    Dr. Eshkevari has been published in numerous peer reviewed scientific journals and has been highlighted in several popular magazines such as National Geographic, and Time Magazine. She is a Fellow in the American Academy of Nursing, the highest honor bestowed on nurses both nationally and internationally.


    Dr. Eshkevari is one of the first ketamine providers in the DMV area; many providers in the area use her protocols after following her in her original Chevy Chase, MD office.


    Interested in understanding more about how ketamine can help your patients?
    Send us an email at team@avestaketaminewellness.com. We would love to introduce you to the mechanics and research supporting IV ketamine infusions for treatment of mood disorders and chronic pain.

How does ketamine work to treat depression?

How does ketamine work in the brain?

Ketamine is an effective alternative to other medications for mood disorders and certain pain disorders for various reasons (safe, minimal side effects, non-addictive, etc). 

It works by affecting neurotransmitters, specifically, those that increase glutamate and gamma-aminobutyric acid (GABA).  When these two neurotransmitters are out of balance, individuals can experience increased mood disorder symptoms, such as heightened anxiety.  Among its other roles, glutamate increases neural connections and influences how someone feels about and responds to their experiences.

Let Us Refer Business To You!

What patients can expect:

  •  Timeline  
    Mood disorder patients start with an induction phase of six-to-eight 45-60 min infusions, spread over a two-to-three week period. 

    Pain patients start with an induction phase of three-to-five consecutive four-hour infusions. 

    The induction phase is  followed by a much more individualized maintenance phase, where the goal is to extend the time between visits until patients feel stable enough to come in only as needed.

  •  Effectiveness  
    On average, patients feel effects within the first 4-5 treatments. 


    With permission, our Avesta team works with the other providers on our patients' care teams to provide optimal care.  We highly recommend continuing regular care with a mental health practitioner throughout treatment with us and often refer patients to providers.


    Most patients benefit from weekly integrative therapy sessions while undergoing their induction


  •  Response  
    The response to ketamine is very individual: some patients feel the benefits right away, while others require all induction infusions, and sometimes more treatments, to notice a change in their mood or pain.

    Our providers assess the patient’s response at each infusion to determine how they are responding overall, and how we can optimize the dosing and infusion rate to achieve the desired response.

Let's Chat About Partnership!

Related from the Blog

Does Ketamine Work for Depression?

[Interview] Dr. Eshkevari on Avesta's Approach to Personalizing Ketamine Therapy

Why Choose Avesta as Your Ketamine Infusion Clinic?

Read Post                 

Patient Testimonials

“Incredible experience and results. I have been living with the effects of complex PTSD for years. The ketamine treatments at Avesta have far exceeded my expectations. 

I feel like I have a new outlook on life, and I feel free. I am treated with the utmost respect each and every visit. I truly believe everyone at Avesta is sincere and genuinely cares. 

I highly recommend them to anyone looking to experience a true positive outcome.”
“I have been receiving ketamine infusions at Avesta since early last year. I was skeptical because receiving "inpatient" and surgical center infusions are a different ballgame. But Avesta has literally saved my life. This is because Dr. E and Deb's team is one of a kind -- they are competent, truly care for the patient, comforting, informative, and simply put: kind. The team is available around the clock for questions and concerns. The atmosphere is relaxing yet professional. If you have chronic pain or are experiencing depression symptoms, I truly suggest Avesta. Ketamine is a big step and I'm not looking back thanks to Dr. E, Deb and their team!”
"I am amazed by Dr. Eshkevari and the entire Avesta staff. 

They are incredibly responsive, attentive, and kind. They genuinely care about their patient's health and well-being, a trait that is too often overlooked in other practices. 

In addition, their facilities are beautiful, inviting, impeccably clean, and organized."

At Avesta Ketamine & Wellness
our mission is to help patients optimize their mental and physical wellness through our many high-end infusion options.
We offer treatments for mood disorders, depression, anxiety, PTSD, pain management, and more. 

Let Us Refer Business To You!

Washington, DC
1400 16th St NW, Washington, DC, Ste. 101
Washington, DC 20036

Mon - Fri 9 am – 7 pm
Sat 9 am – 4 pm
Sun Closed

Bethesda, Maryland
4833 Rugby Ave, Bethesda, MD, Ste. 400
Bethesda, MD 20814

Mon - Fri 9 am – 7 pm
Sat 9 am – 4 pm
Sun Closed

McLean, Virginia
6861 Elm St, McLean, VA, Ste. 3E
McLean, VA 22101

Mon - Fri 9 am – 7 pm
Sat 9 am – 4 pm
Sun Closed